S3 and S4 are low-frequency diastolic sounds that originate in the ventricles. The S3 sound is indicative of increased volume of blood inside the ventricle. An S3 is in a position to be distinguished as either left- or correct-sided by no matter whether or not it increases in intensity with inhalation or exhalation. A correct-sided S3 will improve upon inhalation, and a left-sided S3 will boost with exhalation. There are two typical heart sounds, labeled S1 and S2, and further heart sounds labeled S3 and S4. The clichéd “Lub-Dub” of the heartbeat heard by means of a stethoscope minimizes and understates the complexity of what in fact is occurring.
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